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Gefitinib (ZD1839) is a EGFR tyrosine kinase inhibitor, with IC 50 of 2-37 nM in NR6wtEGFR cells.Quality confirmed by NMR,HPLC.

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Gefitinib is a selective EGFR-TK inhibitor that blocks the growth of GEO colon, ZR-75-1, and MCF-10A Ha-ras breast, and OVCAR-3 ovarian cancer cell lines with IC 50 values of 0.2-0.4 µM. 1 By interfering with the intracellular kinase domain, gefitinib prevents EGFR autophosphorylation and prevents downstream signal transduction. Formulations.

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